منابع مشابه
Splenectomy for haematological disorders.
Splenectomy is therapeutic for a large host of conditions. It is a consequence of expanding the list of disorders and liberalizing the indications for splenectomy in many diseases. Red blood cells disorders: autoimmune hemolytic anemia, hereditary spherocytosis, hemoglobinopathies and thalassemia are prone to splenectomy after failure of medical therapy. A variety of thrombocytopenic disorders ...
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Autoimmune diseases affect around 5% of the population but until recently, although the pathological features of these disorders could be described, there was little idea about the aetiology. Through the development of animal models and the identification of target genes some insight is being gained into the pathogenetic basis of these complex diseases. Blood disorders in which autoantibodies a...
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INTRODUCTION This study aimed to assess the kind of haematological abnormalities that are present in patients with mitochondrial disorders (MIDs) and the frequency of their occurrence. METHODS The blood cell counts of a cohort of patients with syndromic and non-syndromic MIDs were retrospectively reviewed. MIDs were classified as 'definite', 'probable' or 'possible' according to clinical pres...
متن کاملPrimary immunoglobulin deficiency and haematological disorders.
Nine patients with immunoglobulin deficiency and various haematological disorders are presented. In all patients, recurrent infections had antedated the onset of the haematological disorder but, in most, the possibility of primary immunodeficiency had not been considered until after the haematological diagnosis had been established. The recognition of immunodeficiency is important since such pa...
متن کاملA review of gene therapy for haematological disorders.
Gene therapy aims to correct the disease process by restoring, modifying or enhancing cellular functions through the introduction of a functional gene into a target cell. Whilst the concept of gene therapy is simple, the practical reality of translating this new technology to the clinic has proven to be more difficult than first imagined. Recent progress in gene transfer technology has shown im...
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ژورنال
عنوان ژورنال: The Professional Medical Journal
سال: 2018
ISSN: 1024-8919,2071-7733
DOI: 10.29309/tpmj/18.4500